Ligand Binding Assay (LBA) & Biomarker development
- Posted 12 July 2024
- Salary US$47 - US$50 per hour + Medical, Dental, Vision, 401k
- LocationWorcester
- Job type Temporary
- DisciplineLife Science Recruitment
- ReferenceTR/073676_1720815756
- Contact NameRachael Jalbuena
Job description
Scientist II - Ligand Binding Assay (LBA) & Biomarker development
1+ year renewable contract
Worcester, MA
Hourly Pay Rate: $47-50/hr
The Biomarker team of Quantitative Translational ADME Science (QTAS) is seeking for a creative, experienced, and highly motivated scientist to develop bioanalytical biomarker methods and analyze preclinical/clinical samples to support the discovery and development of novel therapies in multiple therapeutic areas.
The ideal candidate should have hands-on experience in a variety of technologies, including but not limited to ligand binding assays (LBA), quantitative PCR, pre-analytics (sample processing steps), etc. He/she will be a key member of a global biomarker bioanalysis team supporting all therapeutic areas with fit-for-purpose methods to enable discovery and development stage decision-making.
Responsibilities
* Develop, validate, transfer, and troubleshoot robust ligand binding biomarker assays on multiple analytical platforms across a variety of sample matrices with supervision.
* Conduct, present and document appropriately compliant biomarker sample testing to support non-clinical and clinical studies.
* Develop effective partnerships with discovery, preclinical safety, clinical pharmacology, and project team representatives in a highly collaborative and innovative environment to deliver high-impact and quality data in a timely manner.
* Evaluate novel, pipeline-enabling, assay technologies to expand capabilities and enhance efficiency.
* Maintain laboratory notebooks in compliance with company policies.
* Strong organization and communication skills, attention to detail, critical thinking, independent, multitasking, desire to learn new techniques and contribute to cutting-edge projects.
Qualifications
* A minimum of 5 years of experience for people who have a bachelor's degree in molecular biology, Biochemistry, or other related fields, or 2-3 years of experience for people who have a Master's degree in related fields.
* Working knowledge of LBA (ELISA, MSD, etc.) biomarker bioanalytical assay development, validation, and sample testing workflows to comply with current regulatory standards and best industry practices.
* Working knowledge in Molecular Biology, especially in DNA/RNA purification and quantitative PCR (qPCR), digital PCR, etc.
* Excellent communication skills, and proven ability to work effectively as a member of a multidisciplinary team.
* Demonstrated capacity to work in a fast-paced environment with meticulous attention to detail, and an ability to handle multiple projects, prioritize work, and meet deadlines.
* Working knowledge of Watson LIMS system is a plus.
Our role in supporting diversity and inclusion
As an international workforce business, we are committed to sourcing personnel that reflects the diversity and values of our client base but also that of Orion Group. We welcome the wide range of experiences and viewpoints that potential workers bring to our business and our clients, including those based on nationality, gender, culture, educational and professional backgrounds, race, ethnicity, sexual orientation, gender identity and expression, disability, and age differences, job classification and religion. In our inclusive workplace, regardless of your employment status as staff or contract, everyone is assured the right of equitable, fair and respectful treatment.
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